The Specialized program courses enable students to experience a more in-depth, focused curriculum. At present, courses here include:
O'Neill also offers a Specialist High Skills Major (S.H.S.M.) in the Arts. The S.H.S.M is open to selected students in Grade 12, and provides some of these particularly keen student artists with the opportunity to work under the guidance of professional artists as they complete public murals in and around the O.C.V.I. community.